![]() ![]() Even though cancer is a leading cause of death in both adults and children, in terms of absolute numbers, pediatric cancer is a relatively rare disease. Although advances in treatment have led to an overall 5-year survival rate for childhood cancers of approximately 80%, cancer is still the second leading cause of death (following accidents) in children aged 5 to 14 years 1. The diagnosis of cancer in children and adolescents is a life-altering event for them and their families. Another goal is to expose the dif- ferent fertility preservation therapeutic options and potential barriers. In this article, the authors aim to characterize what oncofertility is, the effects of cancer and its treatments on the fertility potential of pediatric patients and also on their mental health. Even though there might be several barriers that can negatively affect this process, the presence of a dedicated fertility preservation team may help overcome them. ![]() There is a wide array of fertility preservation options according to gender and pubertal status, and shared decisions must take place at the time of diagnosis. As the number of cancer survivors increases, fertility preservation is becoming an important quality of life issue for many survivors of childhood cancer. the study of interactions between cancer, anti-cancer therapy, fertility, and reproductive health, is an emerging field that addresses cancer patients’ concerns regarding their future reproductive ability. Cancer treatments may affect fertility in different ways.
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